NCT06284330

CHARGE Study: CHoice ARchitecture Genetic tEsting

CHARGE: CHOICE ARCHITECTURE IN GENETIC TESTING

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 108 (actual)
• Sponsor: University of Texas Southwestern Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

CHARGE is a hybrid type I feasibility study to compare a choice architecture intervention for cascade genetic testing to usual care.

Detailed description

CHARGE study contains two arms: Arm 1) Usual care, comprising of standard genetic counseling and education to probands regarding cascade testing; and Arm 2) Direct mailing of a home genetic testing kit to probands' at-risk relatives that can be returned directly to a commercial genetic testing laboratory, including educational information on the importance and cost of cascade testing

Conditions

• Hereditary Cancer

Interventions

Type	Name	Description
OTHER	Enhanced cascade testing	Direct mailed at-home genetic testing kit to probands' relatives.

Timeline

• Start date: 2024-02-16
• Primary completion: 2025-07-31
• Completion: 2025-07-31
• First posted: 2024-02-28
• Last updated: 2025-09-05

Locations

1 site across 1 country: United States