NCT06281418

Postoperative Intraperitoneal Pain Management Following Laparoscopic Cholecystectomy

Postoperative Pain Management Following Laparoscopic Cholecystectomy- Intraperitoneal Granisetron

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Future University in Egypt · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Postoperative pain management is essential and the inability to treat acute pain appropriately in the first 48 postoperative hours represents a risk factor for developing chronic pain. No. study has investigated IP granisetron as an adjuvant to standard care for postoperative pain management in patients undergoing LC.

Detailed description

Postoperative pain is a main challenge for delayed hospital discharge in Laparoscopic cholecystectomy. . Postoperative pain management is essential and the inability to treat acute pain appropriately in the first 48 postoperative hours represents a risk factor for developing chronic pain. Granisetron is frequently used as a premedication to avoid postoperative nausea and vomiting in patients who have undergone general anesthesia. The purpose of this study is evaluating the efficacy and tolerability of IP granisetron on postoperative pain control in patients undergoing LC

Conditions

• Post Operative Pain

Interventions

Type	Name	Description
DRUG	Granisetron 1 Mg/mL Intravenous Solution	2mL intraperitoneal adminstration of granisetron (1 mg/mL)
OTHER	Normal saline	2 ml IP normal saline (0.9% NaCl)

Timeline

• Start date: 2024-02-29
• Primary completion: 2024-12-04
• Completion: 2024-12-04
• First posted: 2024-02-28
• Last updated: 2025-01-10

Locations

1 site across 1 country: Egypt