NCT06280430

Vascular Affection in Behcet Disease

Serum Elafin :A Biomarker in Behcet Disease and Its Relation to Vascular Involvement and Disease Activity

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 90 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 20 Years – 45 Years
• Healthy volunteers: —

Summary

To measure the level of serum elafin in patients with behcet disease and to assess the correlation between serum elafin and vascular affection and their relation with disease activity

Detailed description

Behcet disease is a chronic multi systemic inflammatory disease characterized by recurrent oral and genital ulcers and multiple systemic affection . Elafin is a serine protease inhibitor produced mainly by epithelial cells . previous studies documented the role of serum elafin in pathogenesis of behcet disease.vascular complications may be one if the earliest manifestation leading to the diagnosis of behcet disease.

Conditions

• Behcet Disease and Vascular Involvement

Timeline

• Start date: 2024-03-01
• Primary completion: 2025-03-01
• Completion: 2025-04-01
• First posted: 2024-02-28
• Last updated: 2024-02-28