NCT06276673

The Influences of Single Chamber vs. Multi-chamber Blood Flow Restriction Cuffs

The Influences of Single Chamber vs. Multi-chamber Blood Flow Restriction Cuffs on Post-exercise Arterial Stiffness, Perceptual Responses and Performance

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 35 (estimated)
• Sponsor: Salisbury University · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to investigate the use of single (SC) and multi-chamber (MC) blood flow restriction (BFR) cuff exercise on indices of arterial stiffness, muscle morphology, and participant perception.

Detailed description

Thirty adults aged 18-40 years old will undergo three treatment sessions (control (no BFR), SC BFR, and MC BFR) in a randomized order separated by one week. A familiarization session will also occur one week before starting the treatment period. Each subject will undergo a series of tests including anthropometry, ultrasonography of the carotid artery, applanation tonometry, ultrasonography of the vastus lateralis, blood pressure acquisition, body composition, and maximal strength assessments (1RM). The exercise trial will consist of sets of dumbbell wall squats performed to failure with a 2-seconds concentric and 2-seconds eccentric cadence, at 20% of their 1RM using 60% of the supine limb occlusion pressure (LOP) with 1-minute rest intervals. Assessments will be performed immediately before and after the exercise bout during each treatment session. Two-way ANOVAs will be used to examine the main effects of treatment and treatment-order interaction on pulse wave velocity, muscle cross-sectional area, and perceptual response.

Conditions

• Blood Vessel Disease
• Muscle Edema

Interventions

Type	Name	Description
DEVICE	Delfi	Cuffs will be worn throughout the entire training session. Training session consist of lower intensity wall squats. Four sets of wall squats will be performed to failure. Arterial stiffness and muscle morphological assessments will be conducted before and after the exercise.

Timeline

• Start date: 2024-02-13
• Primary completion: 2024-11-10
• Completion: 2024-12-10
• First posted: 2024-02-26
• Last updated: 2024-02-26

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study