NCT06272279

Neuromodulation With Spinal Stimulation Methods

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: University of Manitoba · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This is a pilot research study to test the protocols needed for transcutaneous spinal electrical stimulation in persons living with spinal cord injury (SCI). Up to 24 participants will be enrolled. A variety of stimulation parameters and outcome measures will be assessed.

Detailed description

Purpose of this project Spinal cord stimulation has the potential to improve motor function recovery after spinal cord injury. Commonly used approaches include low-intensity, direct current (DC) stimulation applied across multiple segments, electrical transcutaneous (ETC) stimulation, and magnetic transcutaneous stimulation (MTC). Objective: to evaluate and compare the voluntary and reflexive motor performance in the same subjects, including people with and without spinal cord injury, after non-invasive spinal cord stimulation interventions. Comparing two different interventions applied in different experimental sessions and the respective sham stimulation is the goal of this study. corticospinal and spinal motor pathways in paraplegics and in non-injured humans will be tested.

Conditions

• Spinal Cord Injuries
• Spinal Cord Injury at C5-C7 Level
• Paraplegia, Spinal
• Paraplegia, Incomplete

Interventions

Type	Name	Description
DEVICE	spinal stimulation-DCS	transcutaneous spinal stimulation by direct current stimulation
OTHER	spinal stimulation-sham DCS	sham transcutaneous spinal stimulation by direct current stimulation
OTHER	spinal stimulation-EPS	transcutaneous spinal stimulation by electrical pulsed stimulation
OTHER	sham spinal stimulation-EPS	sham transcutaneous spinal stimulation by electrical pulsed stimulation

Timeline

• Start date: 2024-03-01
• Primary completion: 2026-01-31
• Completion: 2026-02-15
• First posted: 2024-02-22
• Last updated: 2025-02-10

Locations

2 sites across 1 country: Canada