Trials / Unknown
UnknownNCT06271473
Effect of PPV+ILM Peeling +/- Subretinal Injection of Ringer Lactate in Management of Nontractional Refractory DME
Comparative Study Between Pars Plana Vitrectomy With Internal Limiting Membrane Peeling With or Without Planned Foveal Detachment for Management of Non-tractional Refractory Diabetic Macular Edema
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- Sponsor
- Ain Shams University · Academic / Other
- Sex
- All
- Age
- 40 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
To evaluate the efficacy and safety of combined pars plana vitrectomy and planned foveal detachment through subretinal injection of ringer's solution in patients with non-tractional refractory diabetic macular edema.
Detailed description
In non-tractional cases, PPV allows a more efficient clearance of VEGF and other cytokines from the retina and improves retinal oxygenation by promotion of intraocular fluid currents, and relief of any subclinical tractional forces, thereby reducing DME. To evaluate the efficacy and safety of combined pars plana vitrectomy and planned foveal detachment through subretinal injection of ringer's solution in patients with non-tractional refractory diabetic macular edema.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | vitrectomy + ILM peeling +/- planned foveal detachment via subretinal injection of ringer's solution. | vitrectomy + ILM peeling +/- planned foveal detachment via subretinal injection of ringer's solution. |
Timeline
- Start date
- 2023-08-30
- Primary completion
- 2024-12-30
- Completion
- 2025-06-30
- First posted
- 2024-02-21
- Last updated
- 2024-08-06
Locations
2 sites across 1 country: Egypt
Source: ClinicalTrials.gov record NCT06271473. Inclusion in this directory is not an endorsement.