NCT06269497

TiO2-scaffolds for Alveolar Ridge Preservation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: University of Oslo · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to evaluate the safety of placing TiO2 scaffolds in alveolar ridge and to evaluate if the scaffold material contributes to maintain the anatomy and the volume of the alveolar process after tooth extraction.

Detailed description

The primary objective of the clinical trial is to evaluate the safety of placing TiO2 scaffolds in alveolar ridge. The secondary objectives are; (1) to assess anatomical changes as measured by intraoral digital scanning at the time of extraction, after 6 months. (2) to evaluate soft tissue inflammation at 1, 2, 4, 12 and 24 weeks post-surgery, (3) to assess the preservation of the alveolar ridge following placement of TiO2 scaffold in the alveolae after tooth extraction, (4) to assess bone mineralization and quantitative healing in bone biopsies obtained at implant installation in the preserved site 6 months following treatment.

Conditions

• Alveolar Bone Resorption

Interventions

Type	Name	Description
PROCEDURE	Scaffold placement	The scaffold is placed in the alveola following extraction
RADIATION	CBCT	A Cone Beam Computer Tomography (CBCT) is taken of the area of interest after surgery

Timeline

• Start date: 2021-11-09
• Primary completion: 2022-06-20
• Completion: 2023-08-10
• First posted: 2024-02-21
• Last updated: 2024-02-21

Locations

1 site across 1 country: Norway