NCT06268704

Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection

Particulate Versus Non-Particulate Corticosteroid in Sacroiliac Joint Injection: A Randomized Prospective Study

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 230 (estimated)
• Sponsor: University of New Mexico · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

This study will compare two different corticosteroids (dexamethasone and methylprednisolone) for use in sacroiliac joint injections to treat SI joint pain.

Detailed description

Patients who are screened for inclusion will be randomized into one of two groups; dexamethasone or methylprednisolone. Patients will report their pain immediately after the procedure to confirm the diagnosis of sacroiliac joint pain, then be followed for three months to compare the efficacy and safety of the two medications.

Conditions

• Sacroiliac Joint Dysfunction
• Sacro-Iliac Spondylosis

Interventions

Type	Name	Description
DRUG	Dexamethasone	This is a non-particulate steroid commonly used to treat SI joint pain.
DRUG	Methylprednisolone	This is a particulate steroid commonly used to treat SI joint pain.
DRUG	2% Lidocaine HCl Injection	Lidocaine is a local anesthetic used in SI joint injection procedures to numb the procedure site and helps to confirm SI joint dysfunction when injected with the steroid medication into the SI joint.

Timeline

• Start date: 2024-03-27
• Primary completion: 2027-01-01
• Completion: 2027-05-01
• First posted: 2024-02-20
• Last updated: 2025-11-06

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study