NCT06268444

Infant Sleep and Exposure to Mixture of Chemical Environmental Pollutants

Infant Sleep and Exposure to Mixture of Environmental Pollutants

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: All
• Age: 6 Months
• Healthy volunteers: Not accepted

Summary

During their first year of life, children spend more than half their time sleeping, a function essential to their neurodevelopment. This period of maturation and development of the future adult is considered extremely vulnerable to environmental exposure. During this period, the child\'s diet is mainly provided by breastfeeding, where persistent chemical substances have been found. A cocktail of 19 mostly persistent substances (POPs) present in breast milk has recently been identified as the main contributor to neurodevelopmental risk. However, the reality of their impact on neurophysiological development, in particular on infant sleep, has yet to be assessed. In this project, the sleep of children under 6 months of age will be studied using an actimetry watch worn for 7 days by the child, accompanied by a sleep diary. Exposure to environmental pollutants will be assessed by measuring their presence in the infant\'s milk (breastfeeding) and wearing a silicone bracelet to collect air pollutants. A questionnaire on exposure will complement this evaluation.

Conditions

• Newborn
• Chemical Pollutants Exposure
• Sleep

Interventions

Type	Name	Description
DEVICE	7-day actimetry sleep recording	7-day actimetry sleep recording
OTHER	Determination of environmental pollutants in breast milk	Determination of environmental pollutants in breast milk
OTHER	Measurements of environmental pollutants in indoor air deposited on the bracelet worn by the child	Measurements of environmental pollutants in indoor air deposited on the bracelet worn by the child
OTHER	Continuous recording of the child's temperature for 7 days	Continuous recording of the child\'s temperature for 7 days
OTHER	Use of a sleep diary for 7 days	Use of a sleep diary for 7 days
OTHER	Parental questionnaire of environmental exposure	Parental questionnaire of environmental exposure

Timeline

• Start date: 2024-02-07
• Primary completion: 2026-02-01
• Completion: 2026-02-01
• First posted: 2024-02-20
• Last updated: 2025-05-22

Locations

1 site across 1 country: France