NCT06268275

Comparison of Effects of Scalp Block and Intravenous Esmolol on Hemodynamic Response Following the Skull Pins Application for Elective Supratentorial Craniotomy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Khon Kaen University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to compare hemodynamic response (MAP, SBP, DBP and HR) between scalp block and intravenous esmolol while skull pins application in patients undergoing elective supratentorial craniotomy under general anesthesia.

Conditions

• Hemodynamic Instability

Interventions

Type	Name	Description
PROCEDURE	Scalp block	Receive 30 ml of 0.25% bupivacaine with 1% lidocaine (1:1) with adrenaline 1:200,000 infiltration for 10 minutes before skull pins application.
DRUG	Esmolol	Receive Intravenous esmolol 1 mg/kg bolus over 1 minute before skull pins application

Timeline

• Start date: 2022-09-19
• Primary completion: 2024-02-01
• Completion: 2024-02-13
• First posted: 2024-02-20
• Last updated: 2024-02-20

Locations

1 site across 1 country: Thailand