Trials / Recruiting
RecruitingNCT06266494
Prevention and Treatment of Frostbite Infection With Antimicrobial Pharmacokinetic Analysis
- Status
- Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- Sponsor
- University of Colorado, Denver · Academic / Other
- Sex
- All
- Age
- 18 Years – 99 Years
- Healthy volunteers
- Accepted
Summary
This study will compare the effectiveness of two different treatments for preventing infection from frostbite injuries. These two treatments are A) aloe vera and B) long-acting silver wound dressings. The investigators will also study the safety and effectiveness of Dalbavancin, an FDA approved antibiotic used for treating people who develop frostbite wound infections, as well as evaluate how frostbite damage to individuals' bodies may affect how fast their kidney clear drugs from their systems.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Long-Acting silver dressings | Mepilex Transfer Ag |
| OTHER | Aloe Vera | Dermaid Aloe Vera |
| DRUG | Dalbavancin | 1500mg IV dose |
Timeline
- Start date
- 2024-03-01
- Primary completion
- 2026-05-01
- Completion
- 2026-08-01
- First posted
- 2024-02-20
- Last updated
- 2024-05-13
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT06266494. Inclusion in this directory is not an endorsement.