NCT06265324

Drug-coated Balloon Treatment in Coronary Lesions

Immediate and Midterm Clinical Outcome of Drug Coated Balloon Angioplasty in Different Coronary Artery Lesions in Sohag Governorate

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This study is multicenter registry for drug-coated balloon treatment for de novo and in-stent restenosis lesions

Detailed description

The treatment of coronary lesions triggers processes in vessel walls with different characteristics depending on the revascularization strategy, post-traumatic healing following plain balloon angioplasty triggers vessel recoil and neointimal overgrowth, bare metal or drug eluting stent implantation results in neointimal cell proliferation, scar tissue formation, and ultimately, the generation of neoatherosclerosis Drug-coated balloons(DCBs) were presented two decades ago as an alternative to plain-balloon inflation or subsequent stent implantation in order to overcome in-stent restenosis.Recently, there has been growing evidence that DCBs can also be used off-label to treat de novo lesions in small vessels Therefore, the aim of this study is to evaluate efficacy and safety of drug-coated balloons angioplasty for treatment of de novo and in-stent restenosis lesions

Conditions

• Drug-coated Balloon

Interventions

Type	Name	Description
DEVICE	Angioplasty	Drug-coated balloons angioplasty for treatment of de novo and in-stent restenosis lesions

Timeline

• Start date: 2024-02-10
• Primary completion: 2024-06-10
• Completion: 2025-02-10
• First posted: 2024-02-20
• Last updated: 2024-02-20

Locations

1 site across 1 country: Egypt