NCT06264622

ABG+/GarlACE Effects on Cardiovascular Risk Factors in Subjects With Grade I Hypertension

Dose Response Study of the Effects of a Daily Supplementation With a Black Garlic Extract, ABG+/GarlACE on Cardiovascular Disease Risk Factors in Subjects With Grade I Hypertension

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 180 (estimated)
• Sponsor: Universitat de Lleida · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to evaluate the dose response effect on cardiovascular disease risk factors of a Black Garlic Extract in subjects with Grade I Hypertension. The main questions it aims to answer are: * If the reduction in blood pressure (systolic and diastolic) is in a dose-response manner * If the changes in lipid profile are in a dose-response manner Participants will be randomly assign to a low dose (250 mg/day), high dose (600 mg/day) or placebo of a standardized Garlic Extract (ABG+/GarlACE) during 12 weeks

Conditions

• Hypertension

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Low dose	2 tablets per day during the morning for 12 weeks.
DIETARY_SUPPLEMENT	High dose	2 tablets per day during the morning for 12 weeks.
DIETARY_SUPPLEMENT	Placebo	2 tablets per day during the morning for 12 weeks.

Timeline

• Start date: 2024-02-26
• Primary completion: 2024-10-31
• Completion: 2024-12-31
• First posted: 2024-02-20
• Last updated: 2024-02-20

Locations

1 site across 1 country: Spain