NCT06264596

Epinephrine in Irrigation Fluid for Visualization During Ankle Surgery

The Effect of Epinephrine in Irrigation Fluid for Visualization During Ankle Arthroscopy: A Randomized Blinded Controlled Trial

• Status: Withdrawn
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: The Guthrie Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the effect of epinephrine in irrigation fluid for visual clarity in ankle arthroscopic surgery.

Detailed description

The primary outcomes are: * visual clarity during ankle arthroscopic surgery, which will be evaluated by visual analog scale from 0-10, * and the intraoperative surgeon's discomfort related to bleeding, that will be measured by visual numeric rating scale from 0-3.

Conditions

• Intraoperative Bleeding

Interventions

Type	Name	Description
DRUG	Epinephrine	The epinephrine group will have two 3-L normal saline solution bags prepared for each case with 1 mL of 1:1000 epinephrine in each bag
PROCEDURE	Normal Saline irrigation fluid	The control group will have two 3-L normal saline solution bags prepared with no additive

Timeline

• Start date: 2024-08-01
• Primary completion: 2025-08-01
• Completion: 2026-08-01
• First posted: 2024-02-20
• Last updated: 2024-10-15

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study