NCT06263868

First Observatory of Precocious Puberty.

First Observatory of Precocious and Advanced Puberty in Private Healthcare.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 3,360 (estimated)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: 11 Years
• Healthy volunteers: Accepted

Summary

The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe. A recent Public Health France study published in 2018 reports an increase in the incidence of precocious puberty with geographical heterogeneity. The consequences of these appearances include the early onset of menarche, short adult height and the psychological impact. Due to a lack of studies and additional data, the reasons for this development are difficult to understand. Among current hypotheses, the entanglement with the evolution of our environment is at the forefront: the action of environmental endocrine disruptors and nutritional factors could play a role in the process of early appearance of pubertal signs. The establishment of a national observatory for early and advanced puberty in collaboration with pediatric endocrinologists (on the front line) would allow a reliable and precise field approach, capable of supplementing epidemiological data, which are currently insufficient. The investigators hypothesize that the establishment of an observatory of pubertal advances (early puberty and advanced puberty) in private medicine is possible, with inclusion of at least 75% of eligible patients, and collection of at least 80% of data.

Conditions

• Puberty, Precocious

Timeline

• Start date: 2024-06-26
• Primary completion: 2028-06-26
• Completion: 2028-06-26
• First posted: 2024-02-16
• Last updated: 2026-01-16

Locations

25 sites across 1 country: France