NCT06260878

Short-term Intravenous Fluids for Prevention of Post-ERCP Pancreatitis

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 505 (estimated)
• Sponsor: University of Calgary · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

This study will explore the efficacies of several practical short-term (peri-procedural) intravenous fluid regimens in the prevention of post- endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). PEP is the most common serious ERCP-related adverse event (AE), occurring in 5-15% of patients, and associated with significant morbidity, mortality, and healthcare utilization. Given the current lack of data on effectiveness of short-term fluid regimens in PEP prevention to inform practice, the results of the proposed study have the strong potential to impact ERCP practices worldwide, whether positive or negative.

Conditions

• Post-ERCP Acute Pancreatitis

Interventions

Type	Name	Description
OTHER	Intravenous Ringer's lactate	Intravenous Ringer's lactate

Timeline

• Start date: 2024-11-22
• Primary completion: 2027-12-31
• Completion: 2028-06-30
• First posted: 2024-02-15
• Last updated: 2024-12-20

Locations

1 site across 1 country: Canada