Clinical Trials Directory

Trials / Completed

CompletedNCT06258174

A Study of Two Different Formulations of Pirtobrutinib (LOXO-305) In Healthy Participants

A Phase I, Open-Label, Randomized, 2-Way Crossover Study to Compare the PK of Pirtobrutinib (LOXO-305) Tablets

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
28 (actual)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The main purpose of this study is to compare two different formulations (mixtures) of pirtobrutinib (LOXO-305) in healthy participants. This study will compare how much of each formulation gets into the blood stream and how long it takes the body to remove it. Information about any side effects that may occur will be collected. The study will last up to 65 days.

Conditions

Interventions

TypeNameDescription
DRUGPirtobrutinibAdministered orally.

Timeline

Start date
2021-09-28
Primary completion
2021-12-22
Completion
2021-12-22
First posted
2024-02-14
Last updated
2025-01-13
Results posted
2025-01-13

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06258174. Inclusion in this directory is not an endorsement.