Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06257030

The AMARA (As Much As Reasonably Achievable) Study

The AMARA (As Much As Reasonably Achievable) Study: Radioembolization of Large Inoperable Liver Tumors

Status
Recruiting
Phase
Study type
Observational
Enrollment
100 (estimated)
Sponsor
University Hospital of Patras · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Subjects with large inoperable liver tumors defined as at least 1 lesion larger than 5cm in maximum diameter. For the purposes of the present study, we define the AMARA principle in intensified regional TARE as a planned irradiated tumor dose \>200Gy by the partition model. The purpose of the study is to evaluate the safety and efficacy of Y90 high dose radioembolization for the management of large inoperable liver tumors. In addition, to correlate the safety and efficacy with the post-treatment dosimetry analysis (by MIM Software Inc) based on 90Y-PET/CT imaging.

Conditions

Interventions

TypeNameDescription
DEVICETransarterial Radioembolization(TARE)Transarterial radioembolization is a transcatheter intra-arterial procedure performed by the interventional radiologist for the treatment of primary and secondary hepatic cancers.

Timeline

Start date
2024-02-05
Primary completion
2027-02-05
Completion
2027-02-05
First posted
2024-02-13
Last updated
2024-04-24

Locations

1 site across 1 country: Greece

Regulatory

Source: ClinicalTrials.gov record NCT06257030. Inclusion in this directory is not an endorsement.