NCT06256393

Inflammatory Bowel Disease Cohort in Nantes

Cohorte Nantaise de Maladies Inflammatoires Chroniques Intestinales

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 360 (estimated)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The CELESTE cohort will be a three-center prospective cohort associated with the creation of a biobank including Inflammatory Bowel Diseases (IBD) patients with active disease

Detailed description

The CELESTE cohort will be a prospective cohort of IBD patients followed up at Nantes University Hospital, Jules Verne Clinic (Nantes) and/or Confluent Private Hospital (Nantes). The multicentric nature of the cohort including a tertiary referral center and two secondary care centers is a major asset, enabling the enrolment of a broad spectrum of patients, from those naïve to any immunomodulatory treatment to those refractory to multiple biologic therapies. It will be associated with a multi-omics biobank with the aim of identifying new cellular and molecular signatures of success of the therapeutic strategy at one year.

Conditions

• Inflammatory Bowel Diseases

Interventions

Type	Name	Description
OTHER	Collection of biological samples	Collection of blood samples and intestinal biopsies during a surgery or colonoscopy for disease relapse

Timeline

• Start date: 2025-02-04
• Primary completion: 2028-02-01
• Completion: 2031-02-01
• First posted: 2024-02-13
• Last updated: 2025-02-10

Locations

3 sites across 1 country: France