NCT06253169

HPV DNA Self-sampling in a General Practitioner's Office.

Benefit of Self-sampling for HPV DNA in a General Practitioner's Office to Improve Participation in Cervical Screening - The ASTRA Study.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: Patient Organization Veronica · Other Government
• Sex: Female
• Age: 30 Years
• Healthy volunteers: Not accepted

Summary

One of the limitations of organized cervical screening in the Czech Republic is the lack of participation in preventive gynecological examinations. The aim of the project is to evaluate the benefits of self-sampling for HPV DNA in general practitioners' outpatient clinics to improve population participation in cervical screening.

Detailed description

Organized cervical screening in the Czech Republic has a long-term participation rate of about 56% of the target population. Despite active invitations through health insurance companies, a part of the population is resistant and does not participate in screening visits to gynaecologists in the long term. A significant proportion of such women, however, regularly visit their general practitioner due to other comorbidities. The aim of the ASTRA project is to assess whether an effective way to increase the proportion of women attending cervical screening is to perform self-testing for HPV DNA in the GP's office.

Conditions

• Cervical Cancer
• HPV Infection
• Precancerous Lesion

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	HPV DNA self-test	HPV DNA swab from the cervix performed by the patient herself.

Timeline

• Start date: 2024-03-01
• Primary completion: 2025-03-01
• Completion: 2025-06-01
• First posted: 2024-02-12
• Last updated: 2024-04-23

Locations

2 sites across 1 country: Czechia