NCT06253000

Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium

Comparative Analysis of Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium in Patients With Persistent Atrial Fibrillation

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 158 (estimated)
• Sponsor: Bakulev Scientific Center of Cardiovascular Surgery · Other Government
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Atrial fibrillation (AF) is the cause of 20% of strokes, and the risk of stroke in a person suffering from this arrhythmia increases by 5 times. Ischemic stroke in patients with AF is often fatal and, compared with stroke of other etiology, leads to the most pronounced disability and more often recurs. Accordingly, the risk of death in patients with AF-related stroke is 2 times higher, and treatment costs increase 1.5 times. The main interventional method of treating AF, available in most medical institutions, is the use of radio frequency and/or cryoenergy to eliminate destructive damage to the left atrium (LA). The aim of this study is to compare two different interventional methods and identify predictors of recurrence in patients with persistent and long-term AF.

Conditions

• Stroke
• Acute Cerebrovascular Accident
• Transient Ischemic Attack
• Death
• Atrial Fibrillation Recurrent

Interventions

Type	Name	Description
PROCEDURE	Cryoablation	Cryoablation of the mouths of the pulmonary veins and the posterior wall of the left atrium.
PROCEDURE	Radiofrequency ablation	Radiofrequency ablation of pulmonary veins according to the "box isolation" type using a non-fluoroscopic navigation system.

Timeline

• Start date: 2023-06-10
• Primary completion: 2025-12-30
• Completion: 2026-12-30
• First posted: 2024-02-12
• Last updated: 2025-06-18

Locations

1 site across 1 country: Russia