NCT06252077

Very Low Ketogenic Diet and Energy Expenditure

Effect of Very Low Ketogenic Diet on Energy Metabolism in Women With Obesity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of Pisa · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This study aimed at evaluating the effectiveness of the active phase of a very low-calorie ketogenic diet in females with obesity lasting 28 days on body weight, body composition and energy metabolism using a metabolic chamber.

Detailed description

Patients were recruited at the Obesity and Lipodystrophy Center, University Hospital of Pisa. Enrolled subjects underwent active phase of very low-calorie ketogenic diet within the metabolic chamber from day 0 for a duration of 4 weeks (day 0-28). On days 0, 7, and 28, patients underwent a 24-hour measurement of energy metabolism using the metabolic chamber. On the day of exit from the chamber measurement of body composition was conducted using total-body densitometry (Lunar iDXA; GE Healthcare).

Conditions

• Energy Metabolism

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	very low ketogenic diet	1 month of active phase of very low ketogenic diet

Timeline

• Start date: 2022-06-16
• Primary completion: 2024-01-16
• Completion: 2025-03-16
• First posted: 2024-02-09
• Last updated: 2025-06-04

Locations

1 site across 1 country: Italy