NCT06251349

Comparative Analysis of Radiotherapeutic and Medical Procedures for the Prophylaxis of Heterotopic Ossifications

Comparative Analysis of Radiotherapeutic and Medical Procedures for the Prophylaxis of Heterotopic Ossifications in the Context of Total Hip Arthroplasty

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 512 (actual)
• Sponsor: University of Jena · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Aim of this study is to proof the efficacy of in Jena established prophylaxis of new bone formation aside the skeleton with irradiation and compare it with the common literature. Furthermore we want to compare irradiation treatment with the alternative prophylaxis with analgetics from the NSAID type.

Detailed description

Aim of this retrospective analysis is to compare the incidence of heterotopic ossification one year after total hip arthroplasty with the at our location established concept of irradiation 24h preoperative and incidence in common literature. Furthermore the comparison between irradiated patients and patients treated with NSAIDs.

Conditions

• Heterotopic Ossification
• Hip Arthropathy
• Myositis Ossificans Traumatica, Thigh

Interventions

Type	Name	Description
RADIATION	Radiation	Single dose radiation with 7-8 Gy
DRUG	Diclofenac	postoperative treatment with diclofenac to prevent HO

Timeline

• Start date: 2013-01-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2024-02-09
• Last updated: 2024-02-09

Locations

1 site across 1 country: Germany