NCT06250270

Effects of Casein Protein on Metabolism When Taken Prior to Sleep and in the Morning

• Status: Active Not Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Ohio University · Academic / Other
• Sex: Male
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to investigate the effect of casein protein consumption both prior to sleep as well first thing in the morning on metabolism (increase satiety and appetite, lower resting metabolic rate, and lower blood sugar levels), when compared to nighttime protein or placebo consumption alone. Protein itself is a macronutrient that not only helps the body repair itself, and play a critical role in growth, it also aids in increasing satiety and decreasing appetite. Casein protein specifically is slow digesting dairy protein which may impact the body's metabolism for a longer period than other dairy proteins such as whey. The literature demonstrates nighttime protein ingestion prior to sleep increases metabolic rate and satiety the next morning. However, there appears to be no data on the metabolic effects of protein ingested both at night and in the morning.

Conditions

• Metabolism

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	protein or placebo	casein protein (30g) or placebo (maltodextrin, 30g)

Timeline

• Start date: 2022-10-01
• Primary completion: 2024-05-01
• Completion: 2025-12-31
• First posted: 2024-02-09
• Last updated: 2025-07-30

Locations

1 site across 1 country: United States