Trials / Recruiting
RecruitingNCT06247163
PET-guided Radiotherapy for Patients With Small Cell Lung Cancer.
Prospective PET-guided Radiotherapy for Patients With Small Cell Lung Cancer.
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (estimated)
- Sponsor
- University Hospital, Essen · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
There is a prospective risk-adapted evaluation of the optimal dose of radiotherapy for definitive radiotherapy of locally advanced small cell lung cancer within the corridor recommended as standard therapy according to the current interdisciplinary S3 guideline of the German Cancer Society/Cancer Aid/AWMF
Detailed description
The main objective of this study is to determine whether patients with SCLC who have a metabolically active residual tumor in the fluorodeoxyglucose (FDG) PET/CT scan after two to three cycles of induction chemotherapy have a similarly low local recurrence rate with higher dose. There is a prospective risk-adapted evaluation of the optimal dose of radiotherapy for definitive radiotherapy of locally advanced small cell lung cancer within the corridor recommended as standard therapy according to the current interdisciplinary S3 guideline of the German Cancer Society/Cancer Aid/AWMF. Allocation to PET boost, if confirmed vital tumor rest by PET CT and biopsy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | PET based Raditherapy boost | An Interim PET CT will be performed. If there is residual vital tumor, a higher radiation dose will be applied. |
Timeline
- Start date
- 2024-02-22
- Primary completion
- 2025-06-22
- Completion
- 2029-06-22
- First posted
- 2024-02-07
- Last updated
- 2024-09-27
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT06247163. Inclusion in this directory is not an endorsement.