NCT06246955

Acceptance and Commitment Therapy and Compassion-Based Virtual Group Therapy to Improve Psychological Wellbeing in Patients With Cancer

"Live Fully With Cancer": Assessing the Impact of an Acceptance and Commitment Therapy and Compassion-Based Virtual Group Intervention for Diverse Cancer Patients

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial tests how well acceptance and commitment therapy and compassion based virtual group therapy works to improve psychological wellbeing, such as compassion, understanding, and flexibility, in patients with cancer. Receiving a cancer diagnosis, undergoing cancer treatment, and living with cancer- or treatment-related symptoms have often been found to be associated with elevated distress and decreased quality of life for individuals, even when the disease is stable or in remission. Acceptance and Commitment Therapy (ACT) has demonstrated considerable benefits on individuals' quality of life, psychological flexibility, and amelioration of psychological distress following a cancer diagnosis and in the face of uncertainty, loss, and challenges associated with cancer.

Detailed description

PRIMARY OBJECTIVES: I. To assess if participants perceive compassion and understanding by the provider who facilitates the virtual group intervention. II. To assess if participation in the ACT-based group intervention is associated with increases in patients' self-reported psychological flexibility as well as amelioration in psychological and physical distress. SECONDARY OBJECTIVE: I. To assess if participation in the ACT-based group intervention is associated with increases in patients' self-reported mindfulness, self-compassion, meaning and purpose, and posttraumatic growth. OUTLINE: Patients attend acceptance and commitment virtual group therapy sessions over 1.5 hours each, once a week for 6 weeks. After completion of study treatment, patients are followed up at 1 month.

Conditions

• Hematopoietic and Lymphoid System Neoplasm
• Malignant Solid Neoplasm

Interventions

Type	Name	Description
BEHAVIORAL	Behavioral Intervention: Group Therapy Session	Attend virtual group therapy sessions
OTHER	Survey Administration	Ancillary study

Timeline

• Start date: 2024-01-08
• Primary completion: 2027-12-31
• Completion: 2027-12-31
• First posted: 2024-02-07
• Last updated: 2025-12-11

Locations

1 site across 1 country: United States