Clinical Trials Directory

Trials / Terminated

TerminatedNCT06245941

A Clinical Trial of TQ05105 Tablets Combined With TQB3909 Tablets in the Treatment of Myelofibrosis (MF)

A Phase Ib/II Clinical Trial of TQ05105 Tablets Combined With TQB3909 Tablets in the Treatment of Moderate- and High-risk Myelofibrosis

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
21 (actual)
Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is an open, single-arm, multi-center clinical study designed to evaluate the efficacy and safety of TQ05105 tablets combined with TQB3909 tablets in patients with moderate- and high-risk Myelofibrosis.

Conditions

Interventions

TypeNameDescription
DRUGTQ05105 tabletsTQ05105 is a Janus kinase 1 (JAK1) and Janus kinase 2 (JAK2) Inhibitor
DRUGTQB3909 tabletsTQB3909 is an inhibitor targeting B-cell lymphoma-2 (BCL-2) protein.

Timeline

Start date
2024-05-13
Primary completion
2025-12-30
Completion
2025-12-30
First posted
2024-02-07
Last updated
2026-01-05

Locations

5 sites across 1 country: China

Source: ClinicalTrials.gov record NCT06245941. Inclusion in this directory is not an endorsement.