NCT06244251

Comparison Between Laparoendoscopic Single-site Surgery and Multi-port Laparoscopy in Treating Uterine Fibroids

Comparison of Operational Outcomes and Long-term Benefits Between Laparoendoscopic Single-site Surgery and Multi-port Laparoscopy in Treating Uterine Fibroids

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 5,000 (estimated)
• Sponsor: West China Second University Hospital · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

Myomectomy was preferably applied in females with reproductive requirements, which could be achieved by transumbilical laparoendoscopic single-site surgery (TU-LESS) or multi-port laparoscopic surgery (MPLS). Power morcellation used in MPLS was correlated with unidentified risk of tumor dissemination, especially in cases with accidental surgical findings of uterine sarcoma or leiomyosarcoma. Moreover, TU-LESS was reported to exceed MPLS in fast recovery. Therefore, the aim of this prospective cohort study is to compare the effectiveness of fast recovery and relative risk of tumor dissemination between TU-LESS and MPLS in myomectomy for the treatment of uterine fibroids.

Conditions

• Uterine Fibroid
• Uterine Sarcoma
• Uterine Leiomyosarcoma

Interventions

Type	Name	Description
PROCEDURE	TU-LESS	TU-LESS group will receive TU-LESS for myomectomy; MPLS group will receive MPLS for myomectomy
PROCEDURE	MPLS	Patients with uterine who plan to receive MPLS for myomectomy

Timeline

• Start date: 2023-06-24
• Primary completion: 2026-08-24
• Completion: 2026-12-31
• First posted: 2024-02-06
• Last updated: 2024-02-06

Locations

1 site across 1 country: China