NCT06243042

Vitamin D Serum Levels in Monosymptomatic Enuretic and Non Enuretic Children

A Comparative Study of Vitamin D Serum Levels in Monosymptomatic Enuretic Children and Non-enuretic Children

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 5 Years – 15 Years
• Healthy volunteers: —

Summary

We are group of researchers interested in causes and management of nocturnal enuresis, we embarked on this research on 2020 and we reached promising results regarding the role of vitamin D serum level in etiology and management of monosymptomatic enuresis.

Detailed description

this research was conducted as a comparative study regarding serum vitamin D levels in monosymptomatic enuretic and non enuretic children, also we compared urine osmolality and nocturnal polyuria in both groups and we found that low vitamin D levels are correlated with low nocturnal urine osmolality and increased incidence of nocturnal polyuria

Conditions

• Nocturnal Enuresis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	serum vitamin D	blood sample for serum vitamin D level Vitamin D serum level was measures using the ELISA technique. The Cal Biotech Vitamin D Kit (Mannheim, Germany) was used, which is a solid phase enzyme linked immunoassay (ELISA), based on the principal of competitive binding. Vitamin D deficiency was defined as serum Vit. D below 20 ng/ml.
DIAGNOSTIC_TEST	urine osmolality	nocturnal urine osmolality: Clear instructions for mothers were to let the child void before sleep and every two hours till 8 am. Short intervals were meant to avoid enuretic episodes during calculation of nocturnal urine volume, and if occurred it mandates the repeat of chart on another day. Nocturnal urine collected over the night was tested for osmolality, it was measured in mOsm/kg.
OTHER	Frequency volume chart	volume and frequency from time of sleep till 8 am

Timeline

• Start date: 2020-02-12
• Primary completion: 2020-08-30
• Completion: 2020-09-24
• First posted: 2024-02-06
• Last updated: 2024-02-06

Locations

1 site across 1 country: Egypt