NCT06242015

Ordered Eating and Acute Exercise

The Effect of Ordered Eating on Postprandial Glucose and Substrate Utilization During an Acute Exercise Bout

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: Old Dominion University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

There is well documented evidence that ingesting dietary carbohydrate in large amounts tends to increase postprandial glucose. In healthy populations, this is not necessarily a problem, but continuous exposure to high levels of glucose-hyperglycemia-is a defining characteristic and risk factor for type 2 diabetes mellitus. Consuming a carbohydrate-rich food as the final food in a meal sequence has been shown to significantly reduce postprandial glucose excursions in both diabetes patients and in healthy controls. The exact mechanisms behind this phenomenon are not well understood, but one proposed course is simply that the vegetable and protein already being digested slows the rate of glucose rise. Despite the findings, little-to-no research has examined how manipulating the order of foods in a meal impacts subsequent exercise responses. In this experimental crossover study, each participant will undergo two acute feeding conditions (carbohydrate-rich foods first vs. last in a meal), which will be followed by exercise 60 minutes later. We will observe the effects of meal order on postprandial glucose, substrate/fuel utilization, and subjective perceptions at rest and during 30 minutes of exercise.

Conditions

• Glucose Metabolism Disorders
• Hunger

Interventions

Type	Name	Description
OTHER	Carbohydrate-first meal	Rice (150 grams) eaten first, followed by broccoli (150 grams) and chicken (100 grams)
OTHER	Carbohydrate-last meal	Broccoli (150 grams) and chicken (100 grams) eaten first, followed by rice (150 grams)

Timeline

• Start date: 2024-02-06
• Primary completion: 2024-07-30
• Completion: 2024-07-30
• First posted: 2024-02-05
• Last updated: 2025-08-01

Locations

1 site across 1 country: United States