Clinical Trials Directory

Trials / Completed

CompletedNCT06238817

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis

A Phase 3b, Double-Blind, Multicenter, Randomized, Vehicle-Controlled, Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
241 (actual)
Sponsor
Incyte Corporation · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is being conducted to establish the efficacy of ruxolitinib cream in participants with moderate AD who had an inadequate response to, or are intolerant to, or contraindicated to topical corticosteroid (TCS)s and topical calcineurin inhibitor (TCI)s.

Conditions

Interventions

TypeNameDescription
DRUGRuxolitinib CreamRuxolitinib cream applied topically to the affected area as a thin film twice daily.
DRUGVehicle CreamMatching vehicle cream applied topically to the affected area as a thin film twice daily.

Timeline

Start date
2024-04-26
Primary completion
2025-05-21
Completion
2025-10-17
First posted
2024-02-02
Last updated
2025-10-28

Locations

94 sites across 14 countries: United States, Australia, Belgium, Bulgaria, Canada, France, Germany, Hungary, Italy, Netherlands, Poland, Spain, Switzerland, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT06238817. Inclusion in this directory is not an endorsement.