NCT06236945

HUTT to Assess Cardiac Autonomic Nervous Function

Composite Autonomic Scoring Scale and HUTT to Assess Cardiac Autonomic Nervous Function: A Preliminary Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,122 (estimated)
• Sponsor: The First Hospital of Hebei Medical University · Academic / Other
• Sex: All
• Age: 12 Years – 85 Years
• Healthy volunteers: Accepted

Summary

Autonomic nervous system diseases can cause abnormalities in the circulatory system, leading to malignant arrhythmia and sudden cardiac death. Standardized, operable, and simplified diagnostic indicators are urgently needed to evaluate autonomic nervous function, particularly cardiac autonomic nervous function. The investigators use HUTT in order to provide data support for cardiac autonomic nervous system evaluation.

Detailed description

In this study, 169 samples with vertical tilt test and 24-h Holter ECG data from February 13, 2023 to October 31, 2023 were selected. The AC, DC, and 24-h HRV were compared with the CASS to identify the indicators with the strongest correlation with the CASS sympathetic and vagus nerve scores. The best index was selected, and the score intervals were delimited. The sensitivity and specificity of the defined vagal and sympathetic intervals were analyzed.

Conditions

• Autonomic Nervous System Diseases

Timeline

• Start date: 2024-01-31
• Primary completion: 2025-12-31
• Completion: 2025-12-31
• First posted: 2024-02-01
• Last updated: 2024-09-26

Locations

1 site across 1 country: China