Trials / Recruiting
RecruitingNCT06236789
Observation Study to Evaluate the Efficacy and Safety of Ifosfamide/Mesna in Patients With Metastatic Castration-resistant Prostate Cancer
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (estimated)
- Sponsor
- Yonsei University · Academic / Other
- Sex
- Male
- Age
- 19 Years
- Healthy volunteers
- Not accepted
Summary
Prostate cancer is the 2nd most common cancer in men worldwide. Based on the results of several recent clinical trials, systemic treatments including hormone inhibitors, docetaxel, cabazitaxel, and PARP inhibitors are being used as standard treatment for patients with metastatic castration-resistant prostate cancer. However, there is insufficient research on salvage therapy for patients with metastatic castration-resistant prostate cancer who have failed standard treatment. In this study, the investigators will evaluate the effectiveness and safety of ifosfamide in castration-resistant prostate cancer by analyzing the treatment outcomes of patients who received ifosfamide/mesna treatment as salvage therapy.
Detailed description
1. Retrospective analysis of the treatment outcomes of patients with metastatic castration-resistant prostate cancer who who received ifosfamide/mesna will be conducted. 2. Information regarding demographics (age, gender, and etc.), disease status (stage, metastatic lesion, and etc.), treatment details (administered anticancer drugs, treatment response to drug, and disease progression with progression date), and survival (death with date of death) will be recorded. 3. Statistical method was applied to analyze the correlation between clinical indicators and survival rate.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ifosfamide/mesna | Ifosfamide 2,500 mg/m2/day for 3 days every 3 weeks with mesna until disease progression |
Timeline
- Start date
- 2016-11-01
- Primary completion
- 2026-11-01
- Completion
- 2026-11-01
- First posted
- 2024-02-01
- Last updated
- 2024-02-01
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT06236789. Inclusion in this directory is not an endorsement.