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Active Not RecruitingNCT06235983

A Study of LY3537982 in Chinese Participants With Advanced Solid Tumors

An Open-label, Single-arm, Multicenter, Phase 1 Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Antitumor Activity of LY3537982 in Chinese Patients With KRAS G12C-Mutant Advanced Solid Tumors

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
12 (estimated)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is an open-label, single-arm, multicenter, Phase 1 study of LY3537982 as monotherapy in Chinese participants with KRAS G12C-mutant advanced solid tumors. The main purpose of this study is to determine how much of LY3537982 gets into the bloodstream and how long it takes the body to eliminate it in Chinese participants. The safety, tolerability and preliminary efficacy of LY3537982 will also be evaluated. Approximately 12 patients will be enrolled in this study.

Conditions

Interventions

TypeNameDescription
DRUGLY3537982Administered orally.

Timeline

Start date
2024-02-29
Primary completion
2026-04-01
Completion
2027-04-01
First posted
2024-02-01
Last updated
2025-04-18

Locations

3 sites across 1 country: China

Regulatory

Source: ClinicalTrials.gov record NCT06235983. Inclusion in this directory is not an endorsement.