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Trials / Suspended

SuspendedNCT06235281

Phototherapy and Mogamulizumab in Early Stage MF (PLIGHT)

A Single-Arm, Open-Label, Pilot Study of Concurrent Phototherapy and POTELIGEO (Mogamulizumab-kpkc) in Early Stage Mycosis Fungoides (PLIGHT)

Status
Suspended
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
20 (estimated)
Sponsor
H. Lee Moffitt Cancer Center and Research Institute · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is an open label, single arm, single-center, pilot study of concurrent phototherapy and POTELIGEO (mogamulizumab-kpkc) in early-stage mycosis fungoides.

Conditions

Interventions

TypeNameDescription
DRUGMogamulizumab-KpkcParticipants will receive 8 total cycles of Mogamulizumab-Kpkc over approximately 224 days.
DEVICEPhototherapyParticipants will begin receiving Phototherapy on day 56 and will continue until day 224. Participants with Complete response (CR) or Partial response (PR) to therapy at day 224 will remain on phototherapy maintenance.

Timeline

Start date
2024-01-18
Primary completion
2026-09-01
Completion
2029-09-01
First posted
2024-01-31
Last updated
2026-02-27

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06235281. Inclusion in this directory is not an endorsement.

Phototherapy and Mogamulizumab in Early Stage MF (PLIGHT) (NCT06235281) · Clinical Trials Directory