NCT06234501

Testing the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism

Testing the Potential of High-dose Vitamin B6 Supplements for Sensory Reactivity in Autism

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University of Reading · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial aims to explore the effect of Vitamin B6 supplementation on anxiety sensory hyperreactivity in autistic adults. Researchers will compare a placebo group to high-dose Vitamin-B6 to see if vitamin B6 reduce anxiety and sensory reactivity differences in autism.

Detailed description

The main question it aims to answer is: * Does high-dose Vitamin B6 supplementation reduce sensory hyperreactivity differences in autism? * Does high-dose Vitamin B6 supplementation reduce anxiety differences in autism? * Explore the effects of vitamin B6 on sleep quality, Attention Deficit Hyperactivity Disorder (ADHD) scores, and various visual perception tasks that are indicative of GABAergic activity

Conditions

• Autism

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Pyridoxal 5'-Phosphate (100 mg)	100 mg Pyridoxal 5'-Phosphate tablet once daily with food
OTHER	Placebo	Placebo tablet once daily

Timeline

• Start date: 2024-11-08
• Primary completion: 2026-07-01
• Completion: 2026-07-01
• First posted: 2024-01-31
• Last updated: 2026-03-11

Locations

1 site across 1 country: United Kingdom