NCT06228937

Gut Microbiota in Patients With Limb Lymphedema and Recurrent Lymphangitis

Typing of Gut Microbiota in Patients With Limb Lymphedema and Recurrent Lymphangitis, a Prospective Observational Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Lymphedema is a chronic and progressive disease of the lymphatic vessels which affects about 300 million people worldwide. Patients may experience recurrent soft tissue infection of the limb affected by lymphedema, in terms of erysipelas, lymphangitis or cellulitis. No previous study has ever investigated the possible role of the gut microbiota in the genesis of acute infectious/inflammatory episodes in these patients. Our hypothesis is that lymphedema patients with recurrent soft tissue infections are characterized by pro-inflammatory changes in the microbiota.

Conditions

• Lymphedema
• Microbiota

Interventions

Type	Name	Description
OTHER	analysis of a sample of stool	typing of the gut microbiota from a stool sample

Timeline

• Start date: 2024-02-22
• Primary completion: 2027-10-30
• Completion: 2028-10-30
• First posted: 2024-01-29
• Last updated: 2024-02-28

Locations

1 site across 1 country: Italy