NCT06228378

Comparative Spectroscopic Analysis of Synovial Fluid From the Stable and Unstable Ankle

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A population of patients with chronic ankle instability for whom arthroscopic ligament stabilisation was indicated. Main objective: to use the Raman microspectroscopy technique to characterise the synovial fluid of the unstable ankle in comparison with the synovial fluid of the healthy ankle.

Detailed description

Single-centre, prospective, open-label study of patients undergoing ankle stabilisation surgery. Patients will participate in the study for six months. Three arthrocentheses with synovial fluid sampling will be performed Two at D0: on the healthy ankle and the pathological ankle One at M6: on the operated ankle A follow-up visit will take place 10 days after the arthrocentesis performed at D0 and after the one performed at M6. The purpose of these visits, which are carried out systematically by the centre's doctors as part of the surgical procedures, is to check that there are no complications.

Conditions

• Chronic Ankle Instability

Interventions

Type	Name	Description
OTHER	Raman microspectroscopy	Raman microspectroscopy is a non-destructive method for observing and characterising the molecular composition and external structure of a biological sample based on the phenomenon of inelastic light scattering (Raman effect).

Timeline

• Start date: 2023-09-26
• Primary completion: 2025-01-28
• Completion: 2025-01-28
• First posted: 2024-01-29
• Last updated: 2025-04-06

Locations

1 site across 1 country: France