Trials / Not Yet Recruiting
Not Yet RecruitingNCT06225050
M-2018-334 in Hematological Malignancies
A Single-center Pilot Study Using TCRα/β and CD45RA Depleted Stem Cell Grafts From Haploidentical Donors for Hematopoietic Cell Transplantation in Adults(HAPLO2022)
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 18 (estimated)
- Sponsor
- Miltenyi Biomedicine GmbH · Industry
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
This is a single-center, open-label, single-arm, pilot clinical study using TCRα/β and CD45RA depleted stem cell grafts from haploidentical donors for hematopoietic cell transplantation in 12 to 18 adult patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | CliniMACS Prodigy® LP-TCRα/β-19-45RA (Trial Version) | PBSC grafts from haploidentical donors depleted of TCRaβ+ cells and CD45RA+ cells using CliniMACS Prodigy® will be infused into patients intravenously (IV) |
Timeline
- Start date
- 2026-02-28
- Primary completion
- 2029-02-28
- Completion
- 2029-02-28
- First posted
- 2024-01-25
- Last updated
- 2025-12-03
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT06225050. Inclusion in this directory is not an endorsement.