NCT06223321

The Role of Multislice Computed Tomography in Congenital Heart Diseases in Paediatric Age Group.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 1 Day – 18 Years
• Healthy volunteers: —

Summary

This study aims to evaluate the added value of cardiac multislice Computed Tomography in assessment of CHD in pediatrics as a non-invasive presurgical planning method

Detailed description

All patients will be subjected to the followings: * All children gave an informed consent prior performing the research. * Every child was submitted to full history taking. * Clinical assessment of the patients will be performed in the form of: measuring of vital signs and anthropometric measurements. * Renal function tests(ѕerum creatinine and blood urea). * Patients will be prepared for CT as following: * Calculation of amount of CM and sedations. * The patient will be fasting for 4 hours. * The peripheral venous line will placed usually in a right upper limb vein, exercise if cosurgical . * The patients will be put in a supine position and at the middle of CT gantry. * ECG leads will be put on the chest of the patient. Infants below 6 months will be laid with arms at their side or above their head for image acquisition, positioning the arms above their head is advised, while patients above 6 months of age were positioned with their arms above their head when possible. * CT examination will be done by * 160 MDCT Toshiba Machine or 128 MDCT GE machine or 160 MDCT Philips Machine: * We used the following parameters during cardiac CT scanning: * Pitch of 1.3, helical thickness of 0.5 mm and coverage of 32 cm. * The radiation dose set to 80-100 kvp. * Tube current from 10 to 40 mA/kg. * The gantry rotation speed at 0.35-.4 sec. * ECG gated Retrospective With MA modulation. * Wide FOV. * A scout will be taken and dual-phase injection conducted using non ionized contrast material. The total contrast volume is 1.5-3 ml/kg. * Scanning begins when contrast filled the LV by bolus tracking. * All images were transferred to workstation multiplanar reformation (MPR), maximum (MIP) and minimum (MinIP) intensity projections and volume rendering images will be performed for reporting. * Reporting in sequential approach * Cardiac sidedness * Cardiac position * Three segments , atrial chambers , ventricular chambers and the great arteries (aorta and pulmonary arteries) * Cardiac connections (veno-atrial ,atrio-ventricular and ventriculo-arterial ) * Associated malformation (intra cardiac communications , valvular pathologies) * Aortic arch and its branching pattern * Pulmonary arteries * Pulmonary veins (number and drainage pattern ) * SVC,IVC (their course and draining pattern ) * Systematic veins azygos , hemiazygos and brachiocephalic vein * Coronary arteries * Position of abdominal organs( liver spleen, stomach \& pancrease ) * Secondary changes in cardiac chambers and lung parenchyma * Bony anomalies * Results: Results will be tabulated and assessed statistically and compared to other published results. * Ethical consideration and Study approval: The study protocol will be approved by the ethics committee of Faculty of Medicine, Sohag University.

Conditions

• Congenital Heart Diseases

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Computed Tomography in congenital heart diseases	● CT examination will be done by * 160 MDCT Toshiba Machine or 128 MDCT GE machine or 160 MDCT Philips Machine: * We used the following parameters during cardiac CT scanning: * Pitch of 1.3, helical thickness of 0.5 mm and coverage of 32 cm. * The radiation dose set to 80-100 kvp. * Tube current from 10 to 40 mA/kg. * The gantry rotation speed at 0.35-.4 sec. * ECG gated Retrospective With MA modulation. * Wide FOV. * A scout will be taken and dual-phase injection conducted using non ionized contrast material. The total contrast volume is 1.5-3 ml/kg. * Scanning begins when contrast filled the LV by bolus tracking. * All images were transferred to workstation multiplanar reformation (MPR), maximum (MIP) and minimum (MinIP) intensity projections and volume rendering images will be performed for reporting.

Timeline

• Start date: 2023-01-03
• Primary completion: 2024-06-01
• Completion: 2024-12-01
• First posted: 2024-01-25
• Last updated: 2024-01-25

Locations

1 site across 1 country: Egypt