NCT06220396

CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 30 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate pulmonary capillary wedge pressure (PCWP) and other hemodynamic measurements at rest and during exercise in healthy volunteers across the age spectrum.

Conditions

• Healthy

Interventions

Type	Name	Description
PROCEDURE	Right Heart Catheterization with Hemodynamics and Limited Echocardiogram	Right Heart Catheterization (RHC) with Hemodynamics and Limited Echocardiogram is an invasive procedure that involves insertion of a catheter through a blood vessel in the neck, groin, or arm to the right side of the heart. Hemodynamic measurements such as the blood pressure inside the veins, heart, and arteries as well as measurements of blood flow and how much oxygen is in the blood will be completed during the catheterization procedure. It is a way to see how well the heart is working during your procedure. During the RHC procedure a limited echocardiogram, using ultrasound waves, will be collected to evaluate the structure and function of the heart. All measurements will be conducted at rest and during exercise using a supine cycle ergometer
PROCEDURE	Magnetic Resonance Imaging (MRI)	MRI is a medical imaging technique that uses a magnetic field and computer-generated radio waves to create detailed images of the organs and tissues in your body. CMR Imaging will assess myocardial structure, function, and fat content. An additional limited MRI sequence of the the abdomen and one sequence in the thigh will be used to evaluate for visceral adipose tissue (VAT) as a measurement of body composition.
PROCEDURE	Dual X-ray absorptiometry (DEXA) scan	A DEXA scan measures the amount of fat in the body using an x-ray that measures bone, calcium and fat.

Timeline

• Start date: 2026-01-22
• Primary completion: 2029-01-01
• Completion: 2029-01-01
• First posted: 2024-01-23
• Last updated: 2026-03-05

Locations

1 site across 1 country: United States