NCT06220071

Multicentric European Study In Patients With Vertebral Metastases

Retrospective Multicentric European Study In Patients With Vertebral Metastases (Train-Metastra)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 356 (actual)
• Sponsor: Istituto Ortopedico Rizzoli · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Train-METASTRA is a retrospective study that will be performed in order to collect a large and harmonised amount of clinical and imaging data concerning vertebral metastases, focusing in particular on the risk of fractures. This type of dataset will be created from the medical records of 2000 patients admitted in the last ten years in the four European clinical centers participating in METASTRA project: "COMPUTER-AIDED EFFECTIVE FRACTURE RISK STRATIFICATION OF PATIENTS WITH VERTEBRAL METASTASES FOR PERSONALISED TREATMENT THROUGH ROBUST COMPUTATIONAL MODELS VALIDATED IN CLINICAL SETTINGS", funded by the European Union under the call "HORIZON-HLTH-2022-TOOL-12-two-stage/Computational models for new patient stratification strategies". The project is coordinated by the University of Bologna (UNIBO) (PI prof. Luca Cristofolini) and involves 15 European partners, including Sarl Voisin Consulting Life Sciences VCLS, University of Szeged (Hungary), University of Sheffield (UK) and FrontEndART (Hungary). This type of dataset is not currently available in the literature and it will be pivotal to the development of the METASTRA computational models for the stratification of the risk of fracture of patients affected by spinal metastases.

Conditions

• Spinal Metastases

Interventions

Type	Name	Description
OTHER	Case series review of clinical and radiographic data	Extraction of clinical and radiographic data related to patients' history from medical records

Timeline

• Start date: 2024-02-01
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2024-01-23
• Last updated: 2025-03-19

Locations

3 sites across 3 countries: Germany, Hungary, Netherlands