NCT06219486

The Safe Fast Track Study

Use of D-dimers in the Emergency Department to Identify Adult Patients at Very Low Risk of Mortality for Fast-track Treatment - a Randomized Controlled Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,538 (estimated)
• Sponsor: Odense University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Emergency departments (ED) internationally are treating an increasing number of patients. Most require hospital services but some could be better cared for on alternative pathways. D-dimer has some unique properties. It is non-specific and is elevated in many acute condi- tions; but conversely remains normal in the absence of significant disease. Previous studies have shown that having a normal D-dimer on arrival to the emergency department is associated with a very low risk of 30-day all-cause mortality. The investigators propose a multicenter randomized controlled trial using D-dimer to identify patients at low risk and test if providing this information will change time to discharge disposition by the treating physician.

Conditions

• Emergency Department
• Non-specific Complaints

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	D-dimer	The investigators will measure a D-dimer test on participants and randomize on informing the physician on the value.

Timeline

• Start date: 2024-01-22
• Primary completion: 2025-07-01
• Completion: 2025-08-01
• First posted: 2024-01-23
• Last updated: 2025-04-09

Locations

2 sites across 1 country: Denmark