NCT06218264

BCAAs, Muscle Protein Synthesis and Glucose Uptake

The Role of Branched-chain Amino Acids (BCAAs) in the Stimulation of Skeletal Muscle Protein Synthesis and Glucose Uptake in Healthy Young Volunteers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Wageningen University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The present study aims to quantify the insulin sensitivity and the skeletal muscle protein synthetic response to consuming a test drink containing all amino acids or all amino acids except for BCAAs.

Detailed description

Twenty-eight healthy, young volunteers will receive a stable isotope tracer infusion (7.5h) combined with repeated blood and muscle sampling, to measure muscle protein synthesis rate in the postabsorptive state following ingestion of a drink containing all amino acids (n=14) or all amino acids except for BCAAs (n=14).

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Ingestion of an amino acid supplement	Oral intake of a supplement containing amino acids

Timeline

• Start date: 2024-01-10
• Primary completion: 2026-02-13
• Completion: 2026-02-13
• First posted: 2024-01-23
• Last updated: 2026-02-20

Locations

1 site across 1 country: Netherlands