NCT06216678

The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health

The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health: A Randomized, Crossover, Controlled-feeding Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (estimated)
• Sponsor: Penn State University · Academic / Other
• Sex: All
• Age: 25 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study will examine the effect of a healthy diet containing cottonseed oil compared to healthy diets containing other commonly consumed plant oils on biomarkers of heart and metabolic health after 4 weeks.

Detailed description

This is a 3-period randomized crossover complete feeding study examining if a dietary pattern containing cottonseed oil improves lipids/lipoproteins and other cardiometabolic disease risk factors to a greater extent than a fatty acid matched diet devoid of cottonseed oil and a diet lower in polyunsaturated fatty acids (PUFA) and saturated fatty acids (SFA), but with a matched PUFA:SFA ratio

Conditions

• Cardiovascular Diseases

Interventions

Type	Name	Description
OTHER	Healthy Dietary Pattern with Cottonseed Oil	Cottonseed Oil
OTHER	Healthy Dietary Pattern with Fatty Acid-Matched Plant Oils	Plant oil blend fatty acid matched
OTHER	Healthy Dietary Pattern with PUFA:SFA Ratio-Matched Plant Oil	Plant oil with matched PUFA to SFA ratio

Timeline

• Start date: 2024-09-09
• Primary completion: 2027-12-01
• Completion: 2027-12-01
• First posted: 2024-01-22
• Last updated: 2026-02-02

Locations

1 site across 1 country: United States