Trials / Completed
CompletedNCT06216080
Dynamic Full-Field Optical Coherence Tomography for Structural and Microbiological Characterization of Central Venous Catheter-deposited Biofilm in Critically Ill Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (actual)
- Sponsor
- Centre Hospitalier William Morey - Chalon sur Saône · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, with a significant proportion related to central venous catheters, and an influence on both morbility and mortality. It is now accepted that microbiological biofilm plays a key role on both bacterial and fungal development on inner surface of vascular devices but there is yet a lack of clinical relevant data documenting a causal relation between biofilm formation and bacteremias. We assume that a more precise characterization of central venous catheter-deposited biofilm could help us better understand invasive medical device-related healthcare infections in critically ill patients.
Conditions
- Healthcare Associated Infection
- Critically Ill
- Central Venous Catheter Associated Bloodstream Infection
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | D-FF-OCT analysis of CVC | Dynamic full-field optical coherence tomography analysis of central venous catheter sections to better apprehend strucural characterization of central venous catheter-deposited biofilm |
Timeline
- Start date
- 2023-05-01
- Primary completion
- 2024-12-30
- Completion
- 2025-02-10
- First posted
- 2024-01-22
- Last updated
- 2025-02-18
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT06216080. Inclusion in this directory is not an endorsement.