NCT06214273

Low Level Diode Laser Versus Topical Chamomile in Management of Chemotherapy Induced Oral Mucositis

Evaluation of Low Level Diode Diode Versus Topical Chamomile in Management of Chemotherapy Induced Oral Mucositis: Three Arm Randomized Clinical Trial

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

a three-arm head-to-head randomized clinical trial assessing two of the promising studied interventions, low-level diode laser and topical Chamomile, comparing them to each other's and to conventional therapy in the management of oral mucositis-induced chemotherapy.

Detailed description

The latest MASCC/ISOO Mucositis Guidelines recommend relieving pain, reducing inflammation, and preventing secondary infection as the main pillars in the management of chemotherapy-induced oral mucositis. Accordingly, our comparator will be conventional therapy, including topical anti-inflammatory, topical analgesic, and topical antifungal.

Conditions

• Chemotherapy Induced Oral Mucositis

Interventions

Type	Name	Description
DEVICE	Low level diode laser	diode laser with a wave length range of 800-980 n m and power less than 500 ml
DRUG	Chamomile	Chamomile 3% mucoadhesive gel
DRUG	Ibuprofen analgesic and anti-inflammatory oral gel and miconazole anti fungal oral gel	Topical anti-inflammatory, topical analgesic and topical antifungal

Timeline

• Start date: 2024-04-01
• Primary completion: 2024-07-01
• Completion: 2024-10-01
• First posted: 2024-01-19
• Last updated: 2024-01-23