NCT06213818

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of INCB160058 When Administered Orally to Healthy Adult Participant

A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Dose-Escalation, Drug-Interaction, and Food-Effect Study to Assess the Safety, Tolerability, and Pharmacokinetics of INCB160058 When Administered Orally to Healthy Adult Participants

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 137 (actual)
• Sponsor: Incyte Corporation · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study is being conducted to assess the Safety, Tolerability, and Pharmacokinetics of INCB160058 When Administered Orally to Healthy Adult Participants.

Conditions

• Healthy Participants

Interventions

Type	Name	Description
DRUG	INCB160058	Oral; Immediate release solid tablet
DRUG	Placebo	Oral; Tablet
DRUG	Esomeprazole	Oral; Delayed-release capsule or tablet
DRUG	Famotidine	Oral; Tablet

Timeline

• Start date: 2024-03-14
• Primary completion: 2025-08-19
• Completion: 2025-08-19
• First posted: 2024-01-19
• Last updated: 2025-10-14

Locations

1 site across 1 country: Australia