NCT06211088

Famotidine Versus Placebo in Emergency Pediatric Surgery As a Risk to Postoperative Nausea and Vomiting

Famotidine Versus Placebo in Emergency Pediatric Surgery As a Risk to Postoperative Nausea and Vomiting ꞉ a Comparative Study by Gastric Ultrasound Measurement

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Aswan University Hospital · Academic / Other
• Sex: All
• Age: 2 Years – 13 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate the difference of the gastric volume by quantitative measurements of gastric antrum preoperatively and postoperatively by using 5mg famotidine versus placebo as a risk factor of PONV.

Detailed description

Gastric ultrasound examinations will be performed preoperatively and postoperatively on patients undergoing emergency surgery in pediatric. Gastric cross-sectional area (CSA) will be measured, in order to estimate the gastric volume. The data that will be obtained will be used to evaluate a difference of the gastric volume between the two groups preoperatively and postoperatively and the possible relationship between the gastric volume difference and postoperative adverse event (PONV).

Conditions

• Postoperative Nausea and Vomiting

Interventions

Type	Name	Description
DRUG	famotidine plus10ml normal saline	to evaluate the difference of the gastric volume by quantitative measurements of gastric antrum preoperatively and postoperatively by using 5mg famotidine
OTHER	10ml normal saline	to evaluate the difference of the gastric volume by quantitative measurements of gastric antrum preoperatively and postoperatively by placebo

Timeline

• Start date: 2024-08-01
• Primary completion: 2024-12-30
• Completion: 2025-01-30
• First posted: 2024-01-18
• Last updated: 2025-03-11

Locations

1 site across 1 country: Egypt