NCT06210035

Effects of Heart Rate Oscillations During Meditation on Plasma Biomarkers of Alzheimer's Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 94 (actual)
• Sponsor: University of Southern California · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

In the current study, we will examine how two types of concentration meditation practices affect plasma biomarkers of Alzheimer's Disease (AD). We will also examine the effects of the two types of meditation practices on emotional well-being and episodic memory. Healthy adults aged 18-35 who meet all eligibility criteria will be invited to this study. Participants will be asked to engage in one week of daily meditation practice or no-intervention control task at home. They will also be asked to visit the lab twice, once before and once after the intervention, to provide blood samples to assess plasma biomarkers of AD and to complete emotion questionnaires and a memory test.

Conditions

• Alzheimer Disease

Interventions

Type	Name	Description
BEHAVIORAL	Belly-focus meditation	Participants will engage in concentration meditation for 40 minutes every day for a week. They will focus on the sensations around the belly.
BEHAVIORAL	Belly-focus meditation with slow breathing	Participants will engage in concentration meditation and slow breathing for 40 minutes every day for a week. They will focus on the sensations around the belly while breathing slowly.

Timeline

• Start date: 2024-01-29
• Primary completion: 2024-05-03
• Completion: 2024-05-03
• First posted: 2024-01-18
• Last updated: 2026-01-05
• Results posted: 2026-01-05

Locations

1 site across 1 country: United States